Adopting a more measured, upbeat tone, the Republican president spoke of a "new chapter of American greatness".
Mr Trump condemned recent vandalism of Jewish cemeteries and a hate crime in Kansas that left an Indian man dead.
His primetime address sought to bolster his low approval ratings after a bumpy start to his fledgling presidency.
At the outset of Tuesday night's hour-long speech, Mr Trump tackled recent suspected hate crimes, saying "we are a country that stands united in condemning hate and evil in all its very ugly forms".