After battling through qualifying, Jorge Sampaoli's men are not considered among the strong favourites for Russia 2018.
However, Riquelme – who was capped 51 times by the national team – believes Argentina could contend if Messi performs, having been drawn in Group D alongside Iceland, Croatia and Nigeria.
"We hope that we do well, that the players get well and above all Messi," the Argentinian told El Trece.
"If the latter happens, Argentina will have many chances to win. If Messi is good, nothing is complicated.