Because of Covid restrictions, it will now run from 19 July to 28 August 2022, at the Eventim Apollo, Hammersmith.
Goldberg had been due to star as singer Deloris van Cartier, who hides in a convent, disguised as a nun, after witnessing a murder.
She said: "Sister Act is near and dear to my heart. And I'm disappointed."
Goldberg said: "My producing partners and I will continue to work towards mounting a fantastic production, with an amazing new cast.
