The lockdown at Lae's University of Technology started on Sunday after the deaths of two academics - one the head of the Department of Mechanical Engineering, Dr Gabriel Arpa.
Unitech's administration said the cause of their deaths is yet to be confirmed but both people had Covid-19 symptoms, The National newspaper reported.
Unitech said as an interim precaution, they had decided to suspend all classes for two weeks and impose a total lockdown.